PRODUCTION OF RIBOFLAVIN DEFICIENCY WITH PHENAZINE ANALOGUES OF RIBOFLAVIN

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Regulation of riboflavin-metabolizing enzymes in riboflavin deficiency.

FASS, STEVEN, AND RICHARD S. RIVLIN. Regulation of riboflavinmetabolizing enzymes in ribuj?auin de_ficiency. Am, J. Physiol. 217(4) : 988-99 1. 1969.-The effects of riboflavin deficiency in rats on the hepatic activities of flavokinase, FAD pyrophosphorylase, and FMN phosphatase, three enzymes involved in riboflavin metabolism, have been measured and compared to the hepatic concentrations of FA...

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The Anemia of Human Riboflavin Deficiency.

By MONTAGUE LAisn AND CLARENCE P. ALFREY, Jn. T HE RAPID INDUCTION of experimental riboflavin deficiency in man resulted in the development of a severe anemia which was reversed by riboflavin administration.1’2 In addition to the anemia, the patients developed a deficiency syndrome characterized by sore throat, hyperemia and edema of the pharyngeal and oral mucous membranes, cheilosis, angular ...

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Circular dichroism, self interaction and side chain conformation of riboflavin and riboflavin analogues.

1 V. MASSEY and N. M . ATHERTON, J. biol . Chemistry 237 , 2965 [1962]. 2 B. HOLMSTRÖM, Arkiv. Kern. 22, 281 [1964], 3 M. SCHUMAN and V. MASSEY, Biochim. biophysica Acta [Amsterdam] 227, 500 [1971]. 4 W . M. MOORE and C. BAYLOR, JR., J. Amer . chem. Soc . 91 , 7170 [1969]. this isoalloxazine is extremely slow, as compared to lumiflavin, which allows photoaddition to become predominant in the pr...

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Effects of riboflavin deficiency on the synthesis of ester forms of riboflavin in the rat lens.

A few reports were found on the riboflavin (B2) in the eye tissues in various species (1-3). Flavin compound in the eye of Rana nigromaculata concentrates in the choroid, iris, ciliary body and is not present in other parts. The amount and distribution of flavin compound in the eye varies considerably in different species of frogs (4). The presence of B2 in the lens of haddock (Gadus aeglefinus...

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ژورنال

عنوان ژورنال: Journal of Biological Chemistry

سال: 1944

ISSN: 0021-9258

DOI: 10.1016/s0021-9258(18)71939-x